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Table 2 Summary of analyses for secondary outcomes

From: Antibiotic rotation strategies to reduce antimicrobial resistance in Gram-negative bacteria in European intensive care units: study protocol for a cluster-randomized crossover controlled trial

Outcome

Analysis

Acquisition rates of antibiotic resistant Gram-negative bacteria (ARGNB)

McNemar’s test; Cox proportional hazard regression with random effects for ICUs.

Intensive care unit (ICU)-acquired bacteremia rates

McNemar’s test; Cox proportional hazard regression with random effects for ICUs.

Percentage of appropriate empirical treatment of ICU-acquired bacteremia

McNemar’s test; Generalized linear regression with random effects for ICUs.

Mean length of stay in ICU

Paired t-test; Generalized linear regression with random effects for ICUs.

In-ICU mortality

McNemar’s test; Cox proportional hazard regression with random effects for ICUs.