Table 1 Inclusion and exclusion criteria of ISOGO study

Inclusion criteria

Aged between 40 and 75 years old

Knee osteoarthritis according to the criteria of the American College of Rheumatology

Unilateral medial femorotibial knee osteoarthritis

No corticosteroid or hyaluronic acid infiltration within the 2 months before inclusion

Exclusion criteria

Knee arthroplasty

Radiological end-stage knee osteoarthritis: stage 4 of Kellgren and Lawrence classification

Associated symptomatic femoropatellar osteoarthritis

Language or mental issues preventing the understanding of the protocol

Pregnancy