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A multimedia intervention to enhance recruitment to clinical trials in primary care and community settings: process of development and evaluation


The aim of the MRC START programme is to improve the evidence-base concerning recruitment to trials by nesting innovative recruitment interventions across multiple host trials. This poster presentation will outline the development of a web-based multimedia intervention to be tested in the MRC START programme.


Intervention content was informed by four elements: (a)core themes were generated by team members, (b) a review of factors identified by patients as being determinants of decisions about trial participation; (c) input from members of a patient and public involvement (PPI) forum; (d) input from qualitative experts on patient health experiences (


Nineteen reviews were included. Multimedia interventions offer a platform for learning which can include study-specific information (e.g. study purpose, risks), and generic information (e.g. confidentiality). There was evidence that multimedia interventions improved various outcomes including perceived risk, personal choice and feeling informed.

PPI forum members and qualitative experts developed study-specific components involving bespoke themes such as investigator details and benefits of participation, and generic information components including informed consent, randomisation and confidentiality. Existing video clips of patients discussing their experiences of participation were carefully matched to these components.


The multimedia intervention was developed by a commercial company for use on a range of platforms including desktops and smartphones. The MRC START programme is testing the effects of the intervention on recruitment rates, conducting nested trials of the intervention among existing primary care and community trials. Example websites will be on display with the poster.

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Open Access This article is published under license to BioMed Central Ltd. This is an Open Access article is distributed under the terms of the Creative Commons Attribution License ( ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this article, unless otherwise stated.

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Bower, P., Collier, D., Eldridge, S. et al. A multimedia intervention to enhance recruitment to clinical trials in primary care and community settings: process of development and evaluation. Trials 14 (Suppl 1), P90 (2013).

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