Figure 1

Comparison of cure proportions and 95% CIs obtained from conventional trial design with 100 subjects per arm and logistic regression model of proposed trial design with 100 subjects per arm. The number of weeks of treatment is shown on the x-axis, while the cure proportion is shown on the y-axis. Open boxes and light bars show the point estimate and 95% CI using independent samples, while the closed circles and dark bars show the point estimates and 95% CIs using the proposed regression model and the same number of study subjects as in the independent samples. CI, confidence interval.