Variable | Details | Unit |
---|---|---|
Primary outcomes (Aerobic capacity) | Â | Â |
Peak oxygen uptake (VO2peak) | Peak oxygen uptake in the last 30 s during IET | mL/min, mL/min/kg |
Peak work rate (Ppeak) | Maximal work rate during IET | W |
Peak heart rate (HRpeak) | Maximal heart rate during IET | beats/min |
Peak ventilation rate (VEpeak) | Peak ventilation rate in the last 30 s during IET | L/min |
Peak respiratory rate (Rfpeak) | Peak respiratory rate in the last 30 s during IET | 1/min |
Peak respiratory exchange ratio (RERpeak) | Value of the oxygen uptake and carbon dioxide output relationship at peak oxygen uptake | dimensionless |
Gas exchange threshold (GET) | Oxygen uptake at the point at which carbon dioxide output begins to increase more rapidly in proportion to oxygen uptake during IET. Estimated using the v-slope method and standard gas exchange criteria | mL/min, mL/min/kg |
Oxygen cost of work (ΔVO2/ΔP) | Δ oxygen uptake/Δ work rate | mL/min/W |
Heart rate response (ΔHR/ΔVO2) | Δ heat rate/Δ oxygen uptake | beats/mL/min |
Peak oxygen pulse (VO2peak/HRpeak) | Peak oxygen uptake/peak heart rate | mL/beat |
Time constants of oxygen uptake during on-/off-transition (Ï„) | Time taken for oxygen uptake to reach 63% of its increment magnitude, when the response is modelled as a mono-exponential function during CLT | s |
Steady-state increase in oxygen uptake (ΔVO2) | Steady-state increase in oxygen uptake following a step increase/decrease in exercise intensity during CLT | mL/min, mL/min/kg |
Steady-state increase in heart rate (ΔHR) | Steady-state increase in heart rate following a step increase/decrease in exercise intensity during CLT | beats/min |
Steady-state increase in ventilation rate (ΔVE) | Steady-state increase in minute rate following a step increase/decrease in exercise intensity during CLT | L/min |
Steady-state increase in respiratory rate (ΔRf) | Steady-state increase in respiratory rate following a step increase/decrease in exercise intensity during CLT | 1/min |
Oxygen cost of work during constant load (VO2/P) | Oxygen uptake versus work rate during passive and active constant load phases | mL/min/W |
Secondary outcomes | Â | Â |
RMS deviation of work rate RMSEP | Work rate tracking error during feedback-controlled robotics-assisted treadmill exercise | W |
Gait speed | 10 Meter Walk Test (10MWT) | m/s |
Walking endurance | 6 Minute Walk Test (6MWT) | m |
Standing function | Standardised protocol to assess standing using a force plate | %, mm |
Quality-of-life | Stroke Impact Scale (SIS) | Score |
Feasibility | Criteria for success | 4 scale rating |