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Table 5 Imbalances seen within center across the 1,000 simulations

From: Introduction to a generalized method for adaptive randomization in trials

Differencea

Strong

Medium

Weak

Simple randomization

<−8

   

44

−8

  

2

38

−7

  

2

39

−6

  

21

68

−5

  

61

104

−4

 

2

145

93

−3

 

53

243

158

−2

83

300

349

172

−1

720

706

423

199

0

1372

892

480

201

1

750

684

442

265

2

75

309

347

212

3

 

47

253

217

4

 

7

147

148

5

  

65

125

6

  

11

87

7

  

9

78

8

   

40

>8

   

54

  1. aA difference of −7 indicates that there were seven more participants allocated to treatment group B than treatment group A.