Table 3 Tests/action/questionnaires conducted at baseline, 6 and 12 months

Clinical examination

Cardiovascular/respiratory/gastrointestinal/nervous system/feet

Blood pressure and heart rate

Height, weight, waist circumference

Body-fat content (bio-impedance)

Non-fasting blood collection

GAD, IA-2 and zinc transporter autoantibodies

Full blood count/thyroid function

Liver/renal function

DNA (optional, only at visit 1)

Fasting blood collection

Cholesterol, LDL, HDL, triglycerides

Serum/plasma storage

Inflammation markers

Adiponectin, leptin, IL-6, IL-10, CRP

Meal-stimulated C peptide

Participant attends fasting and drinks Fortisip 240 ml. Venous blood samples collected at time -10, 0, 15, 30, 60, 90, 120 minutes

Questionnaires

International physical activity questionnaire (IPAQ)

Bandura exercise self-efficacy questionnaire

Social support for physical activity scale

Outcome expectations for exercise

Deci and Ryan motivational questions TSRQ

Health care climate questionnaire HCCQ

Pittsburgh sleep quality index (PSQI)

WHO quality of life-BREF

Fear of hypoglycemia survey

BRIEF illness perception

Problem areas in diabetes (PAID)

CES-D

Toole and Glasgow dietary questionnaire

EQ-5D

Activity monitor

Small electronic device worn during waking hours for seven days. Measures physical activity by continually monitoring and recording movements of the body

Fitness test

Estimation of VO2max by submaximal test

Nurse visit

Education on carbohydrate counting and insulin dose adjustment around exercise

Review of exercise diaries

Hypoglycemia management

Motivational support

Focus group for feedback

Obtain feedback on the study