Table 2 Changes in glucose kinetics and insulin sensitivity from before surgery up to the second postoperative day
From: Oral nutrition or water loading before hip replacement surgery; a randomized clinical trial
 Parameter |  Fasting |  Water |  Nutrition |
|---|---|---|---|
Glucose dose (g) | 17.2 (3.8) | 17.4 (2.5) | 17.2 (3.0) |
Plasma glucose at baseline, change (%) | Â | Â | Â |
 Day 0 to Day 1 | +12 (22) | +20 (20) | +16 (17) |
 Day 0 to Day 2 | +25 (15) | +28 (17) | +30 (13) |
Mean glucose during IVGTT (%) | Â | Â | Â |
 Day 0 to Day 1 | +14 (18) | +21 (18) | +19 (15) |
 Day 0 to Day 2 | +21 (21) | +21 (16) | +21 (11) |
Glucose kinetics | Â | Â | Â |
Volume of distribution, change (%) | Â | Â | Â |
 Day 0 to Day 1 | +10 (22) | +12 (25) | +7 (24) |
 Day 0 to Day 2 | 0 (4) | +5 (19) | +6 (22) |
Clearance, change (%) | Â | Â | Â |
 Day 0 to Day 1 | −23 (22) | −23 (28) | −23 (30) |
 Day 0 to Day 2 | −14 (37) | −11 (37) | −9 (46) |
Half-life, T 1/2 , change (%) | Â | Â | Â |
 Day 0 to Day 1 | +57 (62) | +69 (84) | +59 (79) |
 Day 0 to Day 2 | +34 (63) | +42 (74) | +35 (52) |
Insulin sensitivity | Â | Â | Â |
Plasma insulin AUC above baseline (%) | Â | Â | Â |
 Day 0 to Day 1a | −41 (−66 to −5) | −47 (−69 to −10) | −25 (−36 to +33) |
 Day 0 to Day 2a | +23 (−30 to +26) | +66 (+19 to +98) | +55 (+20 to +256) |
Insulin sensitivity change (%) | Â | Â | Â |
 IVGTT Day 0 to Day 1a | −1 (−43 to +20) | +5 (−36 to +47) | −8 (−30 to +15) |
 Day 0 to Day 2a | −43 (−77 to +19) | −38 (−82 to −20) | −51 (−74 to 0) |
 ‘Quicki’ Day 0 to Day 1 | +2 (19) | +2 (8) | −5 (15) |
 Day 0 to Day 2 | −5 (16) | −5 (14) | −15 (16) |