The value of the pragmatic-explanatory continuum indicator summary wheel in an ongoing study: the bullous pemphigoid steroids and tetracyclines study

Table 2 Summary of scores given by BLISTER trial management group members for each domain of the PRECIS wheel

Domain	Score					Mean score (SD)	Median score
	A	B	C	D^a	E^a
Eligibility criteria	74	83	0	80	50	57 (35)	74
Flexibility of the experimental intervention	64	86	85	50	100	77 (20)	85
Practitioner expertise (experimental)	45	100	92	100	90	85 (23)	92
Flexibility of the comparison intervention	64	80	80	50	60	67 (13)	64
Practitioner expertise (comparison)	45	98	90	100	100	87 (24)	98
Follow-up intensity	61	89	50	100	70	74 (20)	70
Outcome	79	58	75	100	100	82 (19)	79
Participant compliance	86	84	20	100	80	74 (31)	84
Practitioner adherence	59	77	70	50	80	67 (13)	70
Primary analysis	74	92	20	50	80	63 (29)	74

A to E represent the members of the trial management group. Scores were transformed onto a 0 to 100 scale with 0 representing the most extreme explanatory end of each domain and 100 representing the most extreme pragmatic end. ^aD and E scored the pragmatism of the trial on each domain out of 10 rather than opting to complete a PRECIS wheel.

ISSN: 1745-6215