Skip to main content

Table 6 Relationship between prior use of cannabis and study drug dosing; summary of ANOVA

From: Assessment of blinding to treatment allocation in studies of a cannabis-based medicine (Sativex®) in people with multiple sclerosis: a new approach

Source

Model 1

Model 2

Model 3

Model 4

Model 5

Baseline severity (BS)

    

0.18

Study (ST)

    

<0.0001

Prior cannabis (PC)

    

0.48

Treatment group (TG

    

<0.0001

TG*PC

0.66

0.70

0.64

0.77

 

TG*ST

0.07

0.06

0.06

  

PC*ST

0.72

0.89

   

TG*PC*ST

0.23

    

Estimated effect of previous cannabis use on dosing (95% CI)

Previous users:

13.9 (13.0 to 14.9)

No previous use:

14.4 (13.6 to 15.1)

Estimated difference:

0.43 (−0.76 to 1.61)