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Table 7 Sensitivity of the overall significance level (α) and power (ω) of pairwise comparisons with the control arm in the STAMPEDE design to the choice of the constant c.

From: Designs for clinical trials with time-to-event outcomes based on stopping guidelines for lack of benefit

c

α

ω

0.4

0.0067

0.822

0.5

0.0084

0.826

0.6

0.0104

0.830

0.7

0.0127

0.835

0.8

0.0153

0.841

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Trials

ISSN: 1745-6215