Table 4 Optic nerve-based measures in treatment group
| Â | Clinically Affected (mean, SD) | Clinically Unaffected (mean, SD) | p |
|---|---|---|---|
Number of optic nerves (n) | 14 | 6 | Â |
LogMAR | 0.15 (0.20) | 0.15 (0.17) | 0.9640 |
Sloan 25% | 0.31 (0.26) | 0.30 (0.20) | 0.9746 |
Sloan 5% | 0.66 (0.35) | 0.53 (0.18) | 0.4282 |
Sloan 1.25% | 1.0 (0.46) | 0.75 (0.15) | 0.1544 |
FM-100 Square-Root Total Error Score | 16.0 (4.4) | 13.5 (2.8) | 0.2188 |
Visual field Mean Deviance | -4.28 (2.04) | -3.04 (2.06) | 0.2267 |
RNFL average thickness (microns) | 72.4 (12.9) | 85.5 (10.2) | 0.0399 |
Macular volume (mm 3 ) | 6.1 (0.5) | 6.6 (0.3) | 0.0624 |
Full field VER latency (milliseconds) | 136.3 (15.2) | 114.8 (7.1) | 0.0045 |
Full-field VER amplitude (microvolts) | 4.8 (1.9) | 4.5 (2.3) | 0.7669 |
Optic nerve area (mm 2 ) | 8.1 (1.3) | 8.9 (1.1) | 0.1961 |
Optic nerve MTR (pu) | 28.4 (2.9) | 31.3 (2.3) | 0.0515 |
Optic nerve DTI Mean Diffusivity (×10 -3 mm 2 /s) | 1.17 (0.29) | 1.25 (0.26) | 0.5415 |
Optic nerve DTI Fractional Anisotropy (×10 3 ) | 298.2 (91.2) | 353.3 (88.6) | 0.2282 |
Optic nerve DTI Radial Diffusivity (×10 -3 mm 2 /s) | 0.99 (0.26) | 1.03 (0.24) | 0.7004 |
Optic nerve DTI Axial Diffusivity (×10 -3 mm 2 /s) | 1.53 (0.42) | 1.70 (0.35) | 0.4012 |