Skip to main content

Table 3 Risk of bias of included trials

From: Failure to report protocol violations in clinical trials: a threat to internal validity?

Methodological Characteristics

Percent (number) of Trials

Details regarding generation of the randomisation sequence

88.75% (71/80)

Reporting of Allocation Concealment



52.5% (42/80)


45.0% (36/80)

   Not maintained

2.5% (2/80)

Use of any type of blinding

58.75% (47/80)

Presentation of results according to ITT

71.25% (57/80)

Loss to follow-up reported by study arm

92.50% (74/80)

  1. Abbreviations: ITT - Intention To Treat.