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Table 3 Risk of bias of included trials

From: Failure to report protocol violations in clinical trials: a threat to internal validity?

Methodological Characteristics Percent (number) of Trials
Details regarding generation of the randomisation sequence 88.75% (71/80)
Reporting of Allocation Concealment  
   Maintained 52.5% (42/80)
   Unclear 45.0% (36/80)
   Not maintained 2.5% (2/80)
Use of any type of blinding 58.75% (47/80)
Presentation of results according to ITT 71.25% (57/80)
Loss to follow-up reported by study arm 92.50% (74/80)
  1. Abbreviations: ITT - Intention To Treat.