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Table 2 Required sample sizes for 80 and 90% power, RR 0.80, 3% losses

From: Beta Agonist Lung Injury TrIal-2 (BALTI-2) trial protocol: A randomised, double-blind, placebo-controlled of intravenous infusion of salbutamol in the acute respiratory distress syndrome

Placebo mortality Salbutamol mortality 80% power 90% power
40% 32% 1164 1558
42% 33.6% 1076 1440
44% 35.2% 998 1334
46% 36.8% 926 1238
48% 38.4% 860 1148
50% 40% 798 1068