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Table 3 number of patients required in the different stages of the trial

From: Cognitive behavioural therapy versus supportive therapy for persistent positive symptoms in psychotic disorders: The POSITIVE Study, a multicenter, prospective, single-blind, randomised controlled clinical trial

 

total

per center

required number of eligible patients (with 75% refusal)

1304

217

number of patients to be included (incl. 20% drop out)

330

55

number of patients to be analysed (ITT, LOCF)

330

55

number of patients to be analysed per protocol

260

44

treatment sessions (CBT and ST)

5530

922

number of visits

4620

770