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Table 3 Intention to treat analysis of the primary and secondary endpoints

From: Intravenous fluid restriction after major abdominal surgery: a randomized blinded clinical trial

  Restricted (n = 30) Standard (n = 32) Absolute Risk Reduction (95% confidence interval)
Postoperative hospital stay (days), mean (SD) 12.3 (12.7) 8.3 (4.5)  
   Median (IQR) 9.0 (6.8–11.3) 7.0 (6.0–9.8) 0.049*
SECONDARY ENDPOINTS    
Postoperative complications 23 13 0.360 (0.133 to 0.588)
- Major complications 12 5 0.244 (0.028 to 0.460)
   - Death 1 0  
   - Cardiac 2 0  
   - Leakage of anastomosis 6 1 0.135 (-0.011 to 0.282)
   - Re-admission 3 4  
- Minor complications 11 8 0.117 (-0.112 to 0.345)
   - Wound infection 5 1  
   - Wound dehiscence 1 0  
   - Infection 0 1  
   - Respiratory 1 0  
   - Bleeding 1 3  
   - Thromboembolism 1 0  
   - Miscellaneous 2 3  
Gastric function    
- First flatus (days) 2.8 (1.3) 2.9 (1.5)  
   Median (IQR) 3 (2–3) 3 (1–4) 0.713*
- First defecation (days) 3.7 (1.3) 3.5 (1.7)  
   Median (IQR) 4 (3–4) 4 (2–5) 0.725*
- Removal nasogastric tube (days) 2.3 (1.3) 2.4 (2.9)  
   Median (IQR) 2 (1–3) 2 (1–2) 0.393*
- Removal of epidural catheter (days) 3.3 (1.5) 3.7 (1.5)  
   Median (IQR) 4 (2–4) 4 (3–4) 0.420*
- Removal of IV catheter (days) 4.9 (2.7) 5.1 (4.5)  
   Median (IQR) 4 (3–5) 4 (3–5) 0.648*
- Normal diet (days) 4.3 (1.9) 4.2 (3.2)  
   Median (IQR) 4 (3–5) 4 (3–4) 0.254*
  1. * = p-values according to Mann-Whitney U test