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Table 1 Clinical Characteristics and Medication Use of Study Participants

From: Elevated levels of matrix metalloprotein-3 in patients with coronary aneurysm: A case control study

 

Group 1 (n = 30)

Group 2 (n = 14)

p

Mean age (yrs)

55.2 ± 10.0

51.8 ± 7.7

NS

Male sex % (n)

70%(21)

64%(9)

NS

Diabetes Mellitus % (n)

13%(4)

14%(2)

NS

Hypertension % (n)

30%(9)

21%(3)

NS

Smoking % (n)

60%(18)

50%(7)

NS

TC (mg/dl)

196.8 ± 31.7

195.1 ± 38.2

NS

TG (mg/dl)

148.7 ± 71.2

151.7 ± 64.0

NS

HDL-C (mg/dl)

46.7 ± 11.8

50.7 ± 13.0

NS

LDL-C (mg/dl)

125.1 ± 28.2

116.7 ± 34.2

NS

hs-CRP (mg/L)

4.78 ± 1.47

4.05 ± 1.53

NS

MMP-1 (ng/ml)

13.63 ± 7.73

12.15 ± 6.27

NS

MMP-3 (ng/ml)

20.23 ± 14.68

11.45 ± 6.55

0.039

Baseline therapy

   

Aspirin

73%(22)

64%(9)

NS

Nitrate

57%(17)

64%(9)

NS

Statin

17%(5)

21%(3)

NS

Number of stenotic vessels

   

One vessel disease

37%(11)

36%(5)

NS

Two vessel disease

50%(15)

43%(6)

NS

Three vessel disease

13%(4)

21%(3)

NS

Reference vessel diameter (mm)

2.95 ± 0.48

-

-

Aneurysm vessel diameter (mm)

4.78 ± 0.93

-

-

Aneurysm/reference vessel ratio

1.6 ± 0.1

-

-

Aneurysm segment

   

Right coronary artery

53%(16)

-

-

Left anterior descending artery

27%(8)

-

-

Left Circumflex artery

30%(9)

-

-

  1. Group 1:Patients with coronary aneurysm, Group 2:Patients without coronary aneurysm, TC:Total cholesterol, TG:Triglyceride, HDL-C:High-density lipoprotein cholesterol, LDL-C:Low-density lipoprotein cholesterol, hs-CRP:High sensitivity C- reactive protein, MMP-1:Matrix metalloproteinase-1, MMP-3:Matrix metalloproteinase-3, NS:Non-significant