https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-9-60
https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-9-57
https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-9-56
https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-9-58
https://trialsjournal.biomedcentral.com/articles/10.1186/1745-6215-9-59