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Page 143 of 208

Estimation bias in survival data within clinical trials that use adaptive seamless designs

Authors: Josephine Khan, Peter Kimani, Nigel Stallard and Ekkehard Glimm

Citation: Trials 2015 16(Suppl 2):P220

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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IntReALL HR and the benefits of adaptive design

Authors: Jane Holmes, Sharon Love, Vaskar Saha and Arend von Stackelberg

Citation: Trials 2015 16(Suppl 2):P216

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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How best to design a clinical trial that is relevant to practice? Applying PRECIS-2, a trial design tool, to primary care trials

Authors: Gordon Forbes, Kirsty Loudon, Shaun Treweek, Stephanie Taylor and Sandra Eldridge

Citation: Trials 2015 16(Suppl 2):P214

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Practicalities of using an adaptive design for decision making within the optima trial: optimal personalized treatment of early breast cancer using multi-parameter tests

Authors: Janet Dunn, Andrea Marshall, Amy Campbell, David Cameron, Helena Earl, Iain Macpherson, Christopher Poole, Daniel Rea, Adele Francis, Victoria Harmer, Adrienne Morgan, Nigel Stallard, Andreas Makris, Luke Hughes-Davies and Robert Stein

Citation: Trials 2015 16(Suppl 2):P212

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Smiley faces and the need for careful planning in trials

Authors: Mike Clarke, Lisa Maguire and Helen McAneney

Citation: Trials 2015 16(Suppl 2):P208

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Impact of retrospective data verification on the results of the academic-led ICON6 trial

Authors: Andrew Embleton, Elizabeth Clark, Stephen Townsend, Laura Farrelly, Cheryl Jones and Richard Kaplan

Citation: Trials 2015 16(Suppl 2):P184

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Do trial managers know when sites will fail to recruit? Preliminary results from the estimating site performance (ESP) study

Authors: Kirsty Shearer, Hanne Bruhn, Anne Duncan, Seonaidh Cotton and Shaun Treweek

Citation: Trials 2015 16(Suppl 2):P182

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Improving quality and efficiency of trial with a novel approach to standard operating procedures (SOPS): case study from a CTU

Authors: Diane Whitham, Lelia Duley and Alex Erven

Citation: Trials 2015 16(Suppl 2):P180

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Overcoming a trial ‘adverse event’: impact and experiences of a temporary suspension of randomisation in clinical trials

Authors: Lynda Constable, Tracey Davidson, Samantha Wileman, Kirsty McCormack, Ruth Thomas, Alison McDonald, Cathryn Glazener and John Norrie

Citation: Trials 2015 16(Suppl 2):P178

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Can site performance be predicted? Results of an evaluation of the performance of a site selection questionnaire in five multicentre trials

Authors: Dawn Coleby, Diane Whitham and Lelia Duley

Citation: Trials 2015 16(Suppl 2):P176

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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The reform study: a case study of embedded trials

Authors: Sarah Cockayne, Joy Adamson, Belen Corbacho, Caroline Fairhurst, Lisa Farndon, Kate Hicks, Anne-Maree Keenan, Sally Lamb, Lorraine Loughrey, Caroline McIntosh, Hylton Menz, Anthony Redmond, Sara Rodgers, Wesley Vernon, Jude Watson and David Torgerson

Citation: Trials 2015 16(Suppl 2):P174

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Correcting for selection bias in two-stage trials with multiple correlated outcomes: application to seamless phase ii/iii clinical trials

Authors: David Robertson, A Toby Prevost and Jack Bowden

Citation: Trials 2015 16(Suppl 2):P145

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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The use of multiple imputation (MI) in cluster randomised trials with suspected missing not at random (MNAR) outcome

Authors: Rebecca Playle, Elinor Coulman, Dunla Gallagher and Sharon Simpson

Citation: Trials 2015 16(Suppl 2):P143

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Analysis techniques in the presence of non-proportional hazards (PH); application to an ovarian cancer RCT with long-term follow-up

Authors: James Morden, Judith Bliss and Rosalind Eeles

Citation: Trials 2015 16(Suppl 2):P141

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Analysis and reporting of individually randomised controlled trials with clustering in one arm only: how should we do it?

Authors: Stephen Walters, Ellen Lee, Laura Flight, Laura Mandefield, Munya Dimario and Annabel Allison

Citation: Trials 2015 16(Suppl 2):P139

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Statistical inference in randomized consent designs in the presence of Hawthorne

Authors: Kyungmann Kim

Citation: Trials 2015 16(Suppl 2):P137

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Under-representation of male patients in breast cancer studies

Authors: Pankaj Mistry, Louise Hiller, Gulnaz Iqbal and Janet Dunn

Citation: Trials 2015 16(Suppl 2):P110

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Incentives and rewards: what do adult populations truly want? Insights from the physical activity loyalty (PAL) scheme

Authors: Helen McAneney, Ruth Hunter, Frank Kee and Mike Clarke

Citation: Trials 2015 16(Suppl 2):P108

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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The NICOLA recruitment trial (NICOLA-RT): can you improve recruitment by making zero cost amendments to the invitation letter?

Authors: Lisa Maguire, Frances Burns and Mike Clarke

Citation: Trials 2015 16(Suppl 2):P106

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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“To have, to hold, from this day forward”: understanding current practice regarding the retention of trial participants

Authors: Anne Daykin, Athene Lane, Carrol Gamble, Anna Kearney, Jane Blazeby, Mike Clarke, Paula Williamson and Ali Heawood

Citation: Trials 2015 16(Suppl 2):P104

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Post-it notes to improve questionnaire response rates in RCTs - findings from a randomised sub-study

Authors: Ada Keding, Helen Lewis, Kate Bosanquet, Simon Gilbody, Hannah Buckley, Helen Tilbrook and David Torgerson

Citation: Trials 2015 16(Suppl 2):P102

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Does size matter? Trial management strategies to increase response rates. The assessment of physical questionnaire size on response rates (APS) sub-study

Authors: Tracey Davidson, Gladys McPherson, Alison McDonald and John Norrie

Citation: Trials 2015 16(Suppl 2):P91

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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The reform patient information sheet sub study - an embedded trial evaluating the enhancement of patient information sheets to improve recruitment

Authors: Sarah Cockayne, Joy Adamson, Peter Bower, Belen Corbacho, Caroline Fairhurst, Lisa Farndon, Kate Hicks, Anne-Maree Keenan, Peter Knapp, Sally Lamb, Lorraine Loughrey, Caroline McIntosh, Hylton Menz, Anthony Redmond, Jo Rick, Sara Rodgers…

Citation: Trials 2015 16(Suppl 2):P87

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Modelling clinical trial recruitment using poisson processes

Authors: Kristian Brock, Christina Yap, Gary Middleton and Lucinda Billingham

Citation: Trials 2015 16(Suppl 2):P85

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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A poetic story: lessons learnt from the world's largest breast cancer window of opportunity study

Authors: Judith Bliss, Alexa Gillman, Lucy Kilburn, James Morden, Kally Sidhu, Maggie Wilcox, Abigail Evans, Christopher Holcombe, Kieran Horgan, Anthony Skene, Raghavan Vidya, John Robertson, Mitch Dowsett and Ian Smith

Citation: Trials 2015 16(Suppl 2):P83

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Do pragmatic trials trade-off internal validity for external validity?

Authors: Kirsty Loudon, Merrick Zwarenstein, Frank Sullivan, Peter Donnan and Shaun Treweek

Citation: Trials 2015 16(Suppl 2):O81

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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What do young people really understand when completing questionnaires? Lessons learnt from developing a questionnaire to measure behavioural outcomes in a sexual health trial

Authors: Lisa Maguire, Aine Aventin, Maria Lohan and Mike Clarke

Citation: Trials 2015 16(Suppl 2):P79

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Recruitment to clinical trials - the use of social media

Authors: Will Storrar, Thomas Brown, Lara Balls, Anoop Chauhan and Carole Fogg

Citation: Trials 2015 16(Suppl 2):O77

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Rapid recruitment of large cohort to support trials in general practice: the role of FARSITE

Authors: Peter Bower, Kelly Howells, Sheila McCorkindale, Lucy Bridges and Mark Sidaway

Citation: Trials 2015 16(Suppl 2):O75

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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What is the effect of patient-reported outcome (PRO) item order on prioritisation of PROs in the development of a core outcome set?

Authors: Katy Chalmers, Kerry Avery, Karen Coulman, Natalie Blencowe, Rhiannon Macefield, Chris Metcalfe, Jane Blazeby and Sara Brookes

Citation: Trials 2015 16(Suppl 2):O73

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Are we getting the whole picture? Measuring outcomes using routinely collected data in long term follow-up: an example from BB:2-6

Authors: Rebecca Cannings-John, Fiona Lugg, Michael Robling and Gwenllian Moody

Citation: Trials 2015 16(Suppl 2):O69

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Outcomes to measure patient safety: the patient reporting and action for a safe environment (PRASE) trial

Authors: Hannah Buckley, Kim Cocks, Rebecca Lawton, Jane O'Hara, Laura Sheard, Claire Marsh, Belen Corbacho Martin, Ian Watt and John Wright

Citation: Trials 2015 16(Suppl 2):P52

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Citation analysis: a new approach to assess the uptake of core outcome sets

Authors: Karen Barnes, Mike Clarke, Jamie Kirkham and Paula Williamson

Citation: Trials 2015 16(Suppl 2):P50

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Assessment of patient-reported adverse events after discharge from hospital in RCTs in gastrointestinal cancer surgery: is there sufficient coverage in existing EORTC questionnaires?

Authors: Kerry Avery, Elaine O’Connell Francischetto, Galina Velikova and Jane Blazeby

Citation: Trials 2015 16(Suppl 2):P48

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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A review of the description of patient withdrawal in trial protocols and patient information sheets (PIS)

Authors: Anna Kearney, Anne Daykin, Ali Heawood, Athene Lane, Jane Blazeby, Mike Clarke, Paula Williamson and Carrol Gamble

Citation: Trials 2015 16(Suppl 2):P46

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Complier-average causal effects for multivariate outcomes: an instrumental variable approach with application to health economics

Authors: Karla DiazOrdaz, Angelo Franchini and Richard Grieve

Citation: Trials 2015 16(Suppl 2):O44

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Introduction of electronic data capture method using participant-completed online web-based follow up questionnaire in mail-based study achieves expected benefits and positive participant feedback

Authors: Jill Barton, Allen Young and Michael Lay

Citation: Trials 2015 16(Suppl 2):P44

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Beyond total treatment effects in RCTs: why we need to measure outcomes at baseline when investigating mediation

Authors: Sabine Landau, Richard Emsley and Graham Dunn

Citation: Trials 2015 16(Suppl 2):O42

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Synthesising participants’ accounts from different mental health trials: the stride study

Authors: Katrina Turner, John Percival, David Kessler and Jenny Donovan

Citation: Trials 2015 16(Suppl 2):O40

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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“You have to keep your nerve on a DMC.” Challenges for data monitoring committees in neonatal intensive care trials: qualitative accounts from the bracelet study

Authors: Claire Snowdon, Diana Elbourne, Peter Brocklehurst, Martin Ward Platt and Robert Tasker

Citation: Trials 2015 16(Suppl 2):O38

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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“It's what we call a randomised control trial” exploring how randomisation is presented by recruiters in RCTs

Authors: Marcus Jepson, Daisy Townsend, Julia Wade, Carmel Conefrey and Jenny Donovan

Citation: Trials 2015 16(Suppl 2):O36

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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When an external pilot is successful, should it be possible to transform it into an internal pilot by continuing recruitment into the full trial is ready? A case study of the cord pilot trial

Authors: Lelia Duley, Angela Pushpa-Rajah, Lucy Bradshaw, Jon Dorling and Eleanor Mitchell

Citation: Trials 2015 16(Suppl 2):P15

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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The quality of reporting of pilot and feasibility cluster randomised trials: a systematic review

Authors: Claire Coleman, Clémence Leyrat and Sandra Eldridge

Citation: Trials 2015 16(Suppl 2):P13

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Exploring non-compliance in a cluster randomised feasibility study to inform the design of the phase III trial

Authors: Lauren Bell, Vipul Jairath and Brennan C Kahan

Citation: Trials 2015 16(Suppl 2):P11

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Trials within trials of interventions to improve recruitment and retention: the experience of York Trials Unit

Authors: David Torgerson and Caroline Fairhurst

Citation: Trials 2015 16(Suppl 2):O9

Content type: Oral presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Addressing treatment contamination in the design and analysis of trials of complex interventions: early results from a systematic review of mental health trials affected by contamination

Authors: Nicholas Magill, Khalida Ismail, Paul McCrone and Sabine Landau

Citation: Trials 2015 16(Suppl 2):P7

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Ingredients, outcomes and mechanisms of change in complex interventions for children with movement limitations: a systematic evidence synthesis

Authors: Niina Kolehmainen, Jennifer McAnuff and Annemarie Tissen-Budde

Citation: Trials 2015 16(Suppl 2):P5

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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Science in a crisis: conducting clinical trials in an emergency

Authors: P Horby

Citation: Trials 2015 16(Suppl 2):I3

Content type: Invited speaker presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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What can we learn from experience? Impact of healthcare provider effects in the total or partial knee arthroplasty trial (TOPKAT)

Authors: Jonathan Cook, Graeme MacLennan, David Murray, Andrew Price, Ray Fitzpatrick, Andrew Carr, Marion Campbell, Helen Campbell, Nigel Arden, Cushla Cooper, Loretta Davies and David Beard

Citation: Trials 2015 16(Suppl 2):P3

Content type: Poster presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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The madness of HIV prevention trials

Authors: S McCormack

Citation: Trials 2015 16(Suppl 2):I1

Content type: Invited speaker presentation Published on: 16 November 2015

This article is part of a Supplement: Volume 16 Supplement 2
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