Skip to main content

Articles

Page 148 of 207

  1. Metabolic syndrome (MetS) has been identified as a major contributor to the development of cardiovascular disease (CVD). Current recommendations for dietary management of people with MetS involve quantitative ...

    Authors: Vanu R. Ramprasath, Sijo J. Thandapilly, Shuo Yang, Anjalika Abraham, Peter J. H. Jones and Nancy Ames
    Citation: Trials 2015 16:489
  2. Emotional disorders (depression and anxiety disorders) are highly prevalent mental health problems. Although evidence showing the effectiveness of disorder-specific treatments exists, high comorbidity rates am...

    Authors: Alberto González-Robles, Azucena García-Palacios, Rosa Baños, Antonio Riera, Ginés Llorca, Francisco Traver, Gonzalo Haro, Vicente Palop, Guillem Lera, José Enrique Romeu and Cristina Botella
    Citation: Trials 2015 16:488
  3. The role of epicardial substrate ablation of ventricular tachycardia (VT) as a first-line approach in patients with ischemic heart disease is not clearly defined. Epicardial ablation as a first-line option is ...

    Authors: Astrid A. Hendriks, Muchtiar Khan, Laszlo Geller, Attila Kardos, Lennart J. de Vries, Sing-Chien Yap, Sip A. Wijchers, Dominic AMJ Theuns and Tamas Szili-Torok
    Citation: Trials 2015 16:487
  4. Worldwide sugar consumption has tripled during the last fifty years. High sugar intake is associated with weight gain and increased incidence of diabetes and has been linked with increased cardiovascular morta...

    Authors: Mark Lown, Richard Fuller, Helen Lightowler, Ann Fraser, Andrew Gallagher, Beth Stuart, Christopher D. Byrne and George Lewith
    Citation: Trials 2015 16:486
  5. Hydraulic dilatation is a novel method of cervical dilatation that is based on continuous controllable dilatation (CCBD) by the pumping of fluid into the balloon extension of the system. The main advantage of ...

    Authors: Petar Arsenijevic, Marko Milosevic, Aleksandar Zivanovic, Biljana Milicic, Branislav Jeremic, Nenad Filipovic, Zoran Protrka, Petar Todorovic and Slobodan Arsenijevic
    Citation: Trials 2015 16:485
  6. The process of obtaining informed consent for participation in randomised controlled trials (RCTs) was established as a mechanism to protect participants against undue harm from research and allow people to re...

    Authors: Katie Gillies, Vikki Entwistle, Shaun P. Treweek, Cynthia Fraser, Paula R. Williamson and Marion K. Campbell
    Citation: Trials 2015 16:484
  7. Degenerative lumbar spinal stenosis is a prevalent condition in adults over the age of 65 and often leads to deconditioning. Although the benefits of surgery outweigh those of conservative approaches, physical...

    Authors: Andrée-Anne Marchand, Margaux Suitner, Julie O’Shaughnessy, Claude-Édouard Châtillon, Vincent Cantin and Martin Descarreaux
    Citation: Trials 2015 16:483
  8. The goals of intentional curative pediatric epilepsy surgery are to achieve seizure-freedom and antiepileptic drug (AED) freedom. Retrospective cohort studies have indicated that early postoperative AED withdr...

    Authors: Kim Boshuisen, Herm J. Lamberink, Monique MJ van Schooneveld, J. Helen Cross, Alexis Arzimanoglou, Ingeborg van der Tweel, Karin Geleijns, Cuno SPM Uiterwaal and Kees PJ Braun
    Citation: Trials 2015 16:482
  9. There are 600 million girls in low and middle income countries (LMICs), many of whom are at great risk for poor health and education. There is thus great need for programs that can effectively improve wellbein...

    Authors: Katherine Sachs Leventhal, Lisa M. DeMaria, Jane Gillham, Gracy Andrew, John W Peabody and Steve Leventhal
    Citation: Trials 2015 16:481
  10. Attention Deficit Hyperactivity Disorder (ADHD) is a common neurodevelopmental disorder characterized by symptoms of inattention and impulsivity and/or hyperactivity and a range of cognitive dysfunctions. Phar...

    Authors: Aida Bikic, James F. Leckman, Jane Lindschou, Torben Ø. Christensen and Søren Dalsgaard
    Citation: Trials 2015 16:480
  11. There has been longstanding interesting in cognitive training for older adults with cognitive impairment. In this study, we will investigate the effects of working memory training, and explore augmentation str...

    Authors: Calvin P. W. Cheng, Sandra S. M. Chan, Arthur D. P. Mak, Wai Chi Chan, Sheung Tak Cheng, Lin Shi, Defeng Wang and Linda Chiu-Wa Lam
    Citation: Trials 2015 16:479
  12. Atrial fibrillation is a common cause of stroke and other morbidity. Adequate treatment with anticoagulants reduces the risk of stroke by 60 %. Early detection and treatment of atrial fibrillation could preven...

    Authors: Steven B. Uittenbogaart, Nicole Verbiest-van Gurp, Petra M. G. Erkens, Wim A. M. Lucassen, J. André Knottnerus, Bjorn Winkens, Henk C. P. M. van Weert and Henri E. J. H. Stoffers
    Citation: Trials 2015 16:478
  13. Treatment of traumatised refugees is one of the fields within psychiatry, which has received little scientific attention. Evidence based treatment and knowledge on the efficiency of the treatment for this comp...

    Authors: Maja Sticker Nordbrandt, Jessica Carlsson, Laura Glahder Lindberg, Hinuga Sandahl and Erik Lykke Mortensen
    Citation: Trials 2015 16:477
  14. Borderline personality disorder is a severe mental disorder that usually has its onset in youth, but its diagnosis and treatment are often delayed. Psychosocial ‘early intervention’ is effective in improving s...

    Authors: Andrew Chanen, Henry Jackson, Sue M. Cotton, John Gleeson, Christopher G. Davey, Jennifer Betts, Sophie Reid, Katherine Thompson and Louise McCutcheon
    Citation: Trials 2015 16:476
  15. Eligibility criteria that result in the exclusion of a substantial number of patients from randomized trials jeopardize the generalizability of treatment effect to much of the clinical population. This is impo...

    Authors: Brittany B. Dennis, Pavel S. Roshanov, Leen Naji, Monica Bawor, James Paul, Carolyn Plater, Guillaume Pare, Andrew Worster, Michael Varenbut, Jeff Daiter, David C. Marsh, Dipika Desai, Zainab Samaan and Lehana Thabane
    Citation: Trials 2015 16:475
  16. Chronic stable angina is a leading cause of death worldwide. Danhong injection, a complementary alternative medicine for chronic stable angina, has been demonstrated to be effective in numerous studies and is ...

    Authors: Peng Qian Wang, Dan Dan Li, Wei Dong, Jun Liu, Ya Nan Yu, Chun Ti Shen, Qi Guang Chen, Bing Wei Chen, Yun Dai Chen and Zhong Wang
    Citation: Trials 2015 16:474
  17. Outpatient chemotherapy is a core treatment for haematological malignancies; however, its toxicities frequently lead to distressing/potentially life-threatening side-effects (neutropenia/infection, nausea/vomi...

    Authors: Sibilah Breen, David Ritchie, Penelope Schofield, Ya-seng Hsueh, Karla Gough, Nick Santamaria, Rose Kamateros, Roma Maguire, Nora Kearney and Sanchia Aranda
    Citation: Trials 2015 16:472
  18. Postoperative surgical site infections cause substantial morbidity, prolonged hospitalization, costs and even mortality, and remain one of the most frequent surgical complications. In prospective trials with a...

    Authors: André L. Mihaljevic, Rebekka Schirren, Tara C. Müller, Victoria Kehl, Helmut Friess and Jörg Kleeff
    Citation: Trials 2015 16:471
  19. International recommendations in favor of screening for vaginal infection in pregnancy are based on heterogeneous criteria. In most developed countries, the diagnosis of bacterial vaginosis is only recommended...

    Authors: Florence Bretelle, Florence Fenollar, Karine Baumstarck, Cécile Fortanier, Jean François Cocallemen, Valérie Serazin, Didier Raoult, Pascal Auquier and Sandrine Loubière
    Citation: Trials 2015 16:470

    The Erratum to this article has been published in Trials 2016 17:83

  20. Previous studies have shown that acupuncture and electroacupuncture (EA) are effective in the treatment of patients with low back pain. However, there is little evidence to support the use of one intervention ...

    Authors: Josielli Comachio, Mauricio Oliveira Magalhães, Thomaz Nogueira Burke, Luiz Armando Vidal Ramos, Gabriel Peixoto Leão Almeida, Ana Paula M. C. C. Silva, Sarah Rúbia Ferreira de Meneses, Jecilene Rosana Costa-Frutuoso, Cinthia Santos Miotto Amorim and Amélia Pasqual Marques
    Citation: Trials 2015 16:469
  21. The success of a clinical trial is often dependant on whether recruitment targets can be met in the required time frame. Despite an increase in research into the benefits of exercise in people with multiple sc...

    Authors: Anouska Carter, Liam Humphreys, Nicky Snowdon, Basil Sharrack, Amanda Daley, Jane Petty, Nicola Woodroofe and John Saxton
    Citation: Trials 2015 16:468
  22. Against the background of increasing use of dental implants, and thus an increasing prevalence of implant-associated complications, a deeper understanding of the biomolecular mechanisms in the peri-implant tis...

    Authors: Katharina Kuhn, Heike Rudolph, Michael Graf, Matthias Moldan, Shaoxia Zhou, Martin Udart, Andrea Böhmler and Ralph G. Luthardt
    Citation: Trials 2015 16:467
  23. Randomised controlled trials (RCTs) of social interventions are often criticised as failing to open the ‘black box’ whereby they only address questions about ‘what works’ without explaining the underlying proc...

    Authors: Farah Jamal, Adam Fletcher, Nichola Shackleton, Diana Elbourne, Russell Viner and Chris Bonell
    Citation: Trials 2015 16:466
  24. The confidence with which researchers can comment on intervention efficacy relies on evaluation and consideration of intervention fidelity. Accordingly, there have been calls to increase the transparency with ...

    Authors: Alison Kate Beck, Amanda Baker, Ben Britton, Chris Wratten, Judith Bauer, Luke Wolfenden and Gregory Carter
    Citation: Trials 2015 16:465
  25. The provision of clinically assisted hydration at the end of life is one of the most contentious issues in medicine, and indeed within the general population. The reasons for contention include: a) the lack of...

    Authors: Andrew Davies, Melanie Waghorn, Julia Boyle, Ann Gallagher and Sigurd Johnsen
    Citation: Trials 2015 16:464
  26. We have recently completed an evaluation of the safety and feasibility of intravenous delivery of autologous bone marrow in patients with progressive multiple sclerosis (MS). The possibility of repair was sugg...

    Authors: Claire M. Rice, David I. Marks, Yoav Ben-Shlomo, Nikos Evangelou, Paul S. Morgan, Chris Metcalfe, Peter Walsh, Nick M. Kane, Martin G. Guttridge, Gail Miflin, Stuart Blackmore, Pamela Sarkar, Juliana Redondo, Denise Owen, David A. Cottrell, Alastair Wilkins…
    Citation: Trials 2015 16:463
  27. Previous research suggests that self-management programs for people with chronic pain improve knowledge and self-efficacy but result in negligible effects on function. This study will investigate the effective...

    Authors: Jordan Miller, Joy C. MacDermid, David M. Walton and Julie Richardson
    Citation: Trials 2015 16:462
  28. Acupuncture is a widely serviced complementary medicine. Although acupuncture is suggested for managing postoperative ileus and pain, supporting evidence is weak. The AcuLap trial is designed to provide high-l...

    Authors: Gangmi Kim
    Citation: Trials 2015 16:461
  29. Medical treatment in patient-centred care in oncology is broadly managed and regulated in terms of guideline development, cancer centres, and quality assurance by cancer registries. In contrast to this quality...

    Authors: Monika Klinkhammer-Schalke, Patricia Lindberg, Michael Koller, Jeremy C. Wyatt, Ferdinand Hofstädter, Wilfried Lorenz and Brunhilde Steinger
    Citation: Trials 2015 16:460
  30. SUN(^_^)D, the Strategic Use of New generation antidepressants for Depression, is an assessor-blinded, parallel-group, multicenter pragmatic mega-trial to examine the optimum treatment strategy for the first- ...

    Authors: Naohiro Yonemoto, Shiro Tanaka, Toshi A. Furukawa, Tadashi Kato, Akio Mantani, Yusuke Ogawa, Aran Tajika, Nozomi Takeshima, Yu Hayasaka, Kiyomi Shinohara, Kazuhira Miki, Masatoshi Inagaki, Shinji Shimodera, Tatsuo Akechi, Mitsuhiko Yamada, Norio Watanabe…
    Citation: Trials 2015 16:459
  31. Mental health disorders are common and disabling for young people because of the potential to disrupt key developmental tasks. Implementation of evidence-based psychosocial therapies in New Zealand is limited,...

    Authors: Mathijs F. G. Lucassen, Karolina Stasiak, Sue Crengle, John R. Weisz, Christopher M. A. Frampton, Sarah Kate Bearman, Ana M. Ugueto, Jennifer Herren, Ainsleigh Cribb-Su’a, Monique Faleafa, Denise Kingi-’Ulu’ave, Jik Loy, Rebecca M. Scott, Morgyn Hartdegen and Sally N. Merry
    Citation: Trials 2015 16:457
  32. The prevention of obesity and improvement of academic achievement in children are concerns of industrialized societies. Obesity has been associated with psychological disorders, including attention deficit hyp...

    Authors: Mairena Sánchez-López, María Jesús Pardo-Guijarro, David Gutiérrez-Díaz del Campo, Pedro Silva, Maria Martínez-Andrés, Roberto Gulías-González, Ana Díez-Fernández, Pablo Franquelo-Morales and Vicente Martínez-Vizcaíno
    Citation: Trials 2015 16:456
  33. Lumbar disc herniation is a major cause of sciatica and low back pain and imposes a heavy burden on both individual and society. While use of pharmacopuncture, a combined form of acupuncture and herbal medicin...

    Authors: Jinho Lee, Joon-Shik Shin, Yoon Jae Lee, Me-riong Kim, Yong-jun Ahn, Ki Byung Park, Michael A. Kropf, Byung-Cheul Shin, Myeong Soo Lee and In-Hyuk Ha
    Citation: Trials 2015 16:455
  34. Exercise during chemotherapy is a promising strategy to reduce fatigue and improve health-related quality of life (HRQoL). It has been shown to be feasible and efficient in various cancers, including advanced-...

    Authors: Cindy Neuzillet, Mathieu Vergnault, Franck Bonnetain and Pascal Hammel
    Citation: Trials 2015 16:454
  35. Extremely premature (birth weight < 1250 g) infants are at high risk for acquiring late-onset sepsis and necrotizing enterocolitis, which are associated with significant mortality and morbidity. Own mother's m...

    Authors: Nancy A. Rodriguez, Maximo Vento, Erika C. Claud, Chihsiung E. Wang and Michael S. Caplan
    Citation: Trials 2015 16:453
  36. Women with breast cancer want to participate in treatment decision-making. Guidelines have confirmed the right of informed shared decision-making. However, previous research has shown that the implementation o...

    Authors: Birte Berger-Höger, Katrin Liethmann, Ingrid Mühlhauser, Burkhard Haastert and Anke Steckelberg
    Citation: Trials 2015 16:452
  37. Evidence suggests that current treatments cannot fully alleviate the burden of disease associated with depression but that prevention approaches offer a promising opportunity to further reduce this burden. Ado...

    Authors: Yael Perry, Alison L. Calear, Andrew Mackinnon, Philip J. Batterham, Julio Licinio, Catherine King, Noel Thomsen, Jan Scott, Tara Donker, Sally Merry, Theresa Fleming, Karolina Stasiak, Aliza Werner-Seidler and Helen Christensen
    Citation: Trials 2015 16:451
  38. Current guidelines recommend that patients with Staphylococcus aureus bloodstream infection (SAB) are treated with long courses of intravenous antimicrobial therapy. This serves to avoid SAB-related complications...

    Authors: Achim J. Kaasch, Gerd Fätkenheuer, Reinhild Prinz-Langenohl, Ursula Paulus, Martin Hellmich, Verena Weiß, Norma Jung, Siegbert Rieg, Winfried V. Kern and Harald Seifert
    Citation: Trials 2015 16:450

    The Update to this article has been published in Trials 2020 21:175

  39. Postoperative delirium (POD) is a manifestation of acute postoperative brain dysfunction that is frequently observed after cardiac surgery. POD is associated with short-term complications such as an increase i...

    Authors: Layth Al Tmimi, Marc Van de Velde, Paul Herijgers, Bart Meyns, Geert Meyfroidt, Koen Milisen, Steffen Fieuws, Mark Coburn, Koen Poesen and Steffen Rex
    Citation: Trials 2015 16:449
  40. Osteoarthritis (OA) is a common cause of pain and disability. Currently available analgesics are often insufficiently effective or have unacceptable adverse effects. Tricyclic antidepressants may offer a usefu...

    Authors: Ben Hudson, Jonathan A. Williman, Lisa K. Stamp, John S. Alchin, Gary J. Hooper, Dee Mangin, Bronwyn F. Thompson and Les Toop
    Citation: Trials 2015 16:448
  41. Tobacco consumption is a preventable risk factor for chronic disease and complicates the treatment of medical conditions. Therefore, the German health insurance company AOK NORDWEST has developed a collaborati...

    Authors: Martin Härter, Anna-Lena Bartsch, Nina Egger, Hans-Helmut König, Levente Kriston, Holger Schulz, Michael Tiemann, Anna Levke Brütt and Angela Buchholz
    Citation: Trials 2015 16:447
  42. Screening physical activity levels is common in trials to increase physical activity in inactive populations. Commonly applied single-item screening tools might not always be effective in identifying those who...

    Authors: Corneel Vandelanotte, Robert Stanton, Amanda L. Rebar, Anetta K. Van Itallie, Cristina M. Caperchione, Mitch J. Duncan, Trevor N. Savage, Richard R. Rosenkranz and Gregory S. Kolt
    Citation: Trials 2015 16:446
  43. The management of an enterocutaneous fistula poses a significant challenge to surgeons and is often associated with a costly hospital stay and long-term discomfort. The use of fibrin glue in the fistula tract ...

    Authors: Xiuwen Wu, Jianan Ren, Gefei Wang, Jianzhong Wang, Feng Wang, Yueping Fan, Yuanxin Li, Gang Han, Yanbing Zhou, Xiaofei Song, Bin Quan, Min Yao and Jieshou Li
    Citation: Trials 2015 16:445
  44. Inflammatory bowel disease, comprising Crohn’s disease and ulcerative colitis, is a life-long currently incurable illness. It causes bouts of acute intestinal inflammation, in an unpredictable relapsing-remitt...

    Authors: Christine Norton, Lesley B. Dibley, Ailsa Hart, Julie Duncan, Anton Emmanuel, Charles H. Knowles, Natasha Stevens, Helen Terry, Azmina Verjee, Sally Kerry and Natalia Hounsome
    Citation: Trials 2015 16:444
  45. Venous leg ulcers are common, chronic wounds that are painful and reduce quality of life. Compression therapy is known to assist in the healing of venous leg ulceration. Supervised exercise training that targe...

    Authors: Garry A. Tew, Jonathan Michaels, Helen Crank, Geoff Middleton, Anil Gumber and Markos Klonizakis
    Citation: Trials 2015 16:443
  46. Infancy is a period of rapid growth and habit formation and hence could be a critical period for obesity prevention. Excess weight gain during infancy is associated with later obesity and formula-fed babies ar...

    Authors: Rajalakshmi Lakshman, Fiona Whittle, Wendy Hardeman, Marc Suhrcke, Ed Wilson, Simon Griffin and Ken K Ong
    Citation: Trials 2015 16:442
  47. Repetitive Transcranial Magnetic Stimulation (rTMS) has been proposed as a new tool in neurological rehabilitation of victims of traumatic brain injury (TBI). However, its usefulness to treat this condition ha...

    Authors: Iuri Santana Neville, Cintya Yukie Hayashi, Simone Alves El Hajj, Ana Luiza Costa Zaninotto, Juliana Perez Sabino, Leonardo Moura Sousa Jr, Marcia Mitie Nagumo, André Russowsky Brunoni, Barbara Dal Forno Silva Shieh, Robson Luis Oliveira Amorim, Manoel Jacobsen Teixeira and Wellingson Silva Paiva
    Citation: Trials 2015 16:440

Annual Journal Metrics

  • 2022 Citation Impact
    2.5 - 2-year Impact Factor
    2.5 - 5-year Impact Factor
    0.827 - SNIP (Source Normalized Impact per Paper)
    0.814 - SJR (SCImago Journal Rank)

    2023 Speed
    33 days submission to first editorial decision for all manuscripts (Median)
    129 days submission to accept (Median)

    2023 Usage 
    6,282,238 downloads
    5,569 Altmetric mentions