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This randomised controlled trial (RCT) with two parallel arms will evaluate the efficacy of an internet-delivered six-lesson 10-week cognitive behavioural therapy (iCBT) intervention for posttraumatic stress d...
The proportion of pregnant women who have a caesarean section shows a wide variation across Europe, and concern exists that these proportions are increasing. Much of the increase in caesarean sections in recen...
The per-protocol effect is the effect that would have been observed in a randomized trial had everybody followed the protocol. Though obtaining a valid point estimate for the per-protocol effect requires assum...
For the surgical treatment of recurrent primary spontaneous pneumothoraces (rPSP) different operative therapies are applied to achieve permanent freedom from recurrence.
Single-incision laparoscopic surgery (SILS) is an emerging minimally invasive surgery to reduce abdominal incisions. However, despite the increasing clinical application of SILS, no evidence from large-scale, ...
Cognitive behaviour therapy for insomnia (CBT-I) is a well-established treatment; however, the evidence is largely limited to homogenous samples. Although emerging research has indicated that CBT-I is also eff...
The diagnosis of Pulmonary Embolism (PE) in the emergency department (ED) is crucial. As emergency physicians fear missing this potential life-threatening condition, PE tends to be over-investigated, exposing ...
Undergoing an extraction has been shown to pose a significantly increased risk for the development of chronic apprehension for dental surgical procedures, disproportionate forms of dental anxiety (that is, den...
Recruitment to trials evaluating the effectiveness of childhood obesity management interventions is challenging. We report our experience of recruitment to the Families for Health study, a randomised controlle...
Rates of perinatal depression (antenatal and postnatal depression) in South Asia are among the highest in the world. The delivery of effective psychological treatments for perinatal depression through existing...
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
This article is part of a Supplement: Volume 16 Supplement 3
Packed red blood cell (PRBC) transfusion is required in hematology patients treated with chemotherapy for acute leukemia, autologous (auto) or allogeneic (allo) hematopoietic stem cell transplantation (HSCT). ...
Low back pain (LBP) is a common health problem and a substantial part of LBP is presumed to be attributable to degeneration of the intervertebral disc. For patients suffering from intractable discogenic LBP, t...
Poor nutrition in the first months after oesophago-gastric resection is a contributing factor to the reduced quality of life seen in these patients. The aim of this pilot and feasibility study was to ascertain...
Niacin induces the release of vasodilating prostaglandins, for which receptors are present within the pulmonary arterial circulation. We hypothesized that immediate-release niacin would reduce right ventricula...
With the global escalation of type 2 diabetes and evidence consistently showing that its onset can be prevented or delayed by changing lifestyle behaviours, there is an urgent need to translate practical, affo...
Chronic subdural hematoma (CSDH) is a common disease that is more prevalent in older people. Surgical intervention is a safe treatment of choice. However, the recurrence rate is relatively high and the outcome...
Idiopathic macular holes are an important cause of blindness. They have an annual incidence of 8 per 100,000 individuals, and prevalence of 0.2 to 3.3 per 1000 individuals with visual impairment. The condition...
About 90 % of all persons with mild Alzheimer’s disease experience neuropsychiatric symptoms, most frequently apathy, depression, anxiety and irritability. These symptoms are associated with greater morbidity,...
Acupuncture is considered to be an effective and safe treatment for obese and overweight patients, although high-quality evidence regarding the effects of acupuncture on obesity are not conclusive. The aim of ...
Pelvic floor muscle training is effective and recommended as first-line therapy for female patients with stress urinary incontinence. However, standard pelvic floor physiotherapy concentrates on voluntary cont...
Noncompliance to treatment assignment is an inevitable occurrence in randomized clinical trials (RCTs). Intention to treat (ITT) is generally considered the best method for addressing noncompliance in RCTs. Al...
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
The Erratum to this article has been published in Trials 2016 17:109
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
This article is part of a Supplement: Volume 16 Supplement 2
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