Volume 14 Supplement 1

2nd Clinical Trials Methodology Conference: Methodology Matters

Meeting abstracts

Publication of this supplement was funded by the 2nd Clinical Trials Methodology Conference.

2nd Clinical Trials Methodology Conference: Methodology Matters. Go to conference site.

Edinburgh, UK18-19 November 2013

Page 6 of 6

Measuring impact of systematic reviews using individual participant data: evidence from clinical guidelines

Authors: Claire Vale, Larysa Rydzewska, Lesley Stewart, Maroeska Rovers, Jonathan Emberson and François Gueyffier

Citation: Trials 2013 14(Suppl 1):P123

Content type: Poster presentation Published on: 29 November 2013
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Development of a method for adjusting trial results for biases in meta-analysis

Authors: Rebecca Turner, Jelena Savovic, Hayley Jones, Jonathan Sterne, Nicky Welton and Julian Higgins

Citation: Trials 2013 14(Suppl 1):P124

Content type: Poster presentation Published on: 29 November 2013
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Meta-analysis of mean differences from randomized trials with nested clustering

Authors: Rebecca Walwyn

Citation: Trials 2013 14(Suppl 1):P125

Content type: Poster presentation Published on: 29 November 2013
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Using systematic reviews to identify research gaps - a case study: mIBG for the treatment of neuroblastoma in children

Authors: Jayne Wilson, Jenny Gains, Veronica Moroz, Mark Gaze and Keith Wheatley

Citation: Trials 2013 14(Suppl 1):P126

Content type: Poster presentation Published on: 29 November 2013
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'No collaboration, no trial; why collaborator opinion matters'

Authors: Claire Cochran

Citation: Trials 2013 14(Suppl 1):P127

Content type: Poster presentation Published on: 29 November 2013
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Trial steering committees for randomised controlled trials: updating and redeveloping guidance and terms of reference informed by current practice and experience

Authors: EJ Conroy, S Lewis, A Lane, MR Sydes, J Norrie, G Murray, NL Harman and C Gamble

Citation: Trials 2013 14(Suppl 1):P128

Content type: Poster presentation Published on: 29 November 2013
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Developing effective and efficient study specific training to enable rapid study start up

Authors: Lynda Constable, Alison McDonald and Cathryn Glazener

Citation: Trials 2013 14(Suppl 1):P129

Content type: Poster presentation Published on: 29 November 2013
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The need for speed? Examples from a randomised controlled trial in the emergency setting

Authors: Seonaidh Cotton, Tracey Davidson, Nishat Siddiqi and Michael Frenneaux

Citation: Trials 2013 14(Suppl 1):P130

Content type: Poster presentation Published on: 29 November 2013
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Minimising bias in an un-masked, pragmatic rct comparing two treatment pathways for glaucoma by the use of decision support software - the light trial experience

Authors: Gus Gazzard, Haogang Zhu, Amanda Lewis and Neil Nathwani

Citation: Trials 2013 14(Suppl 1):P131

Content type: Poster presentation Published on: 29 November 2013
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Rapid set up of research centres in a trial in an evolving research governance world

Authors: Sharon Ruddock, Bipin Bhakta, Amanda Lilley-Kelly, Suzanne Hartley and Lorna Barnard

Citation: Trials 2013 14(Suppl 1):P132

Content type: Poster presentation Published on: 29 November 2013
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File notes and breach reports: when are they appropriate?

Authors: Alison McDonald, Seonaidh Cotton and John Norrie

Citation: Trials 2013 14(Suppl 1):P133

Content type: Poster presentation Published on: 29 November 2013
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Impact of training for site staff recruiting into trials of rare skin diseases: experiences from stop gap and blister

Authors: Eleanor Mitchell, Lelia Duley, Hywel Williams and Diane Whitham

Citation: Trials 2013 14(Suppl 1):P134

Content type: Poster presentation Published on: 29 November 2013
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Reporting adverse events in a large community-based public health trial (building blocks): what gets reported and how does it vary?

Authors: Gwenllian Moody, Eleri Owen-Jones, Rebecca Cannings-John, Carolyn Wallace, Mike Robling and Julia Sanders

Citation: Trials 2013 14(Suppl 1):P135

Content type: Poster presentation Published on: 29 November 2013
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Using routinely collected data to enhance long term follow up data: an example from the building blocks trial

Authors: Rebecca Cannings-John and Michael Robling

Citation: Trials 2013 14(Suppl 1):P136

Content type: Poster presentation Published on: 29 November 2013
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Simple tools for projecting patient recruitment

Authors: Paul Silcocks

Citation: Trials 2013 14(Suppl 1):P137

Content type: Poster presentation Published on: 29 November 2013
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Update on the temper study: targeted monitoring, prospective evaluation and refinement

Authors: Sally Stenning, Nicola Joffe, Priyanka Batra, Catrin Jones, Carlos Diaz Montana, Nancy Tappenden and Sarah Meredith

Citation: Trials 2013 14(Suppl 1):P138

Content type: Poster presentation Published on: 29 November 2013
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Central statistical monitoring in multicentre clinical trials: developing statistical approaches for analysing key risk indicators

Authors: Elsa Valdes-Marquez, Jemma C Hopewell, Jane Armitage and Martin Landray

Citation: Trials 2013 14(Suppl 1):P139

Content type: Poster presentation Published on: 29 November 2013
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Streamlining the study start up process

Authors: Samantha Wileman and John Norrie

Citation: Trials 2013 14(Suppl 1):P140

Content type: Poster presentation Published on: 29 November 2013
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Trial data management: lessons from a large orthopedic trial

Authors: Erik Lenguerrand, Vikki Wylde, Rachael Gooberman-Hill, Sian Noble, Elsa Marques, Paul Dieppe and Ashley Blom

Citation: Trials 2013 14(Suppl 1):P141

Content type: Poster presentation Published on: 29 November 2013
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The thistle study: a stepped-wedge clustered trial of an intrapartum emergencies training package in Scottish maternity units

Authors: Erik Lenguerrand, Graeme MacLennan, Dimitrios Siassakos, Timothy Draycott, Siladitya Bhattacharya and John Norrie

Citation: Trials 2013 14(Suppl 1):P142

Content type: Poster presentation Published on: 29 November 2013
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Statistical methodology for recurrent events, with application to major trials in heart failure

Authors: Jennifer Rogers and Stuart Pocock

Citation: Trials 2013 14(Suppl 1):P143

Content type: Poster presentation Published on: 29 November 2013
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2nd Clinical Trials Methodology Conference: Methodology Matters

Meeting abstracts

Measuring impact of systematic reviews using individual participant data: evidence from clinical guidelines

Development of a method for adjusting trial results for biases in meta-analysis

Meta-analysis of mean differences from randomized trials with nested clustering

Using systematic reviews to identify research gaps - a case study: mIBG for the treatment of neuroblastoma in children

'No collaboration, no trial; why collaborator opinion matters'

Trial steering committees for randomised controlled trials: updating and redeveloping guidance and terms of reference informed by current practice and experience

Developing effective and efficient study specific training to enable rapid study start up

The need for speed? Examples from a randomised controlled trial in the emergency setting

Minimising bias in an un-masked, pragmatic rct comparing two treatment pathways for glaucoma by the use of decision support software - the light trial experience

Rapid set up of research centres in a trial in an evolving research governance world

File notes and breach reports: when are they appropriate?

Impact of training for site staff recruiting into trials of rare skin diseases: experiences from stop gap and blister

Reporting adverse events in a large community-based public health trial (building blocks): what gets reported and how does it vary?

Using routinely collected data to enhance long term follow up data: an example from the building blocks trial

Simple tools for projecting patient recruitment

Update on the temper study: targeted monitoring, prospective evaluation and refinement

Central statistical monitoring in multicentre clinical trials: developing statistical approaches for analysing key risk indicators

Streamlining the study start up process

Trial data management: lessons from a large orthopedic trial

The thistle study: a stepped-wedge clustered trial of an intrapartum emergencies training package in Scottish maternity units

Statistical methodology for recurrent events, with application to major trials in heart failure

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