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Table 2 Administration of study measures by assessment period

From: Efficacy of dapagliflozin in the treatment of HFrEF with obstructive sleep apnea syndrome (DAHOS study): study protocol for a multicentric, prospective, randomized controlled clinical trial

Research phase

Screening and randomization

Treatment period

Interview

1

2

3

4

Research date

 − 7–0

28 ± 2

56 ± 4

84 ± 6

Baseline information

 Informed consent

   

 General information

   

 History

   

 Physical examination

Treatment

 Inclusion/exclusion criteria

   

 Combined medication

 Compliance

 

 Completion of research

   

Inclusion/exclusion criteria

 PSG

   

 Echocardiography

   

Security index

 Blood routine

  

 Urine routine

  

 Blood biochemical

  

 Electrocardiogram

  

 Adverse event assessment

 

Outcome

 AHI

  

 Epworth Somnolence Scale (ESS)

 Echocardiography

  

 NT-proBNP

  

 Quality of life as measured by the Minnesota Living with Heart Failure Questionnaire

 EQ—5D—3L

    

 LSpO2

  

 Inflammatory factors