Effects of programmed flexor–extensor alternating electrical acupoint stimulation on upper limb motor functional reconstruction after stroke: study protocol for a double-blind, randomized controlled trial

Table 3 Schedule of study procedures

Study period	Washout	Observation	Baseline	Treatment			Follow-up
Timepoint	≦7 days	3-7 days	0 day	1 day*	3 week◈	3 week^⊙	1 month	3 month
Patients
Informed consent	×
Eligibility screening			×
Patients’essential information			×
Allocation			×
Primary outcome
sEMG			×	×	×	×
EEG			×	×	×	×
sEMG synergy-coherence analysis			×	×	×	×
EEG power spectrum analysis			×	×	×	×
Secondary outcomes
MBI			×			×	×	×
CSS			×			×	×	×
FMA-U			×			×	×	×
MMT			×			×	×	×
Brunnstrom			×			×	×	×
Healthy controls
Informed consent			×
Eligibility screening			×
Patients’ essential information			×
Primary outcome
sEMG			×
EEG			×
sEMG synergy-coherence analysis			×
EEG power spectrum analysis			×
Blinding assessment				×	×	×
Adjuvant therapy				×	×	×	×	×
Adverse events				×	×	×	×	×

ISSN: 1745-6215