Screening period | Intervention and observation period | |||||
---|---|---|---|---|---|---|
-7 ~ -1 day | Preoperative | Intraoperative | Sugery ended | Duration of stay in PACU | 24 h postoperatively | |
Informed consent | X | |||||
Medical history | X | |||||
Physical examination | X | |||||
Demographics | X | |||||
ECG | X | X | ||||
Blood cell testa | X | X | ||||
Liver and kidney functionb | X | |||||
Inclusion /exclusion criteria | X | |||||
Randomization | X | |||||
Intraoperative narcotic analgesics | X | |||||
Non-steroidal antiinflammatory drugs(NSAIDs) | X | |||||
Trial drug | X | |||||
Neostigmine | X | |||||
Atropine | X | |||||
Electronic intravenous analgesia pump | X | X | X | |||
Extubation time | X | |||||
Aldrete score | X | |||||
VAS score | X | X | ||||
RASS score | X | |||||
Montreal orientation score | X | |||||
Remedial analgesic sufentanilc | X | |||||
PONV | X | X | ||||
Pruritus | X | X | ||||
Combination medicationd | X | X | X | X | X | X |
Adverse events | X | X | X | X | X | X |