Table 1 Inclusion and exclusion criteria for trial participants
Inclusion criteria | 21 years of age or older |
Spherical equivalent of ≤ -6.00 D | |
Refractive cylinder ≤ -2.00 D | |
Best spectacle-corrected visual acuity (BCVA) of 20/40 or better | |
Spherical or cylindrical error has progressed at − 0.50 D or less per year before the baseline measurement | |
Contact lens must have been removed at least 2 weeks before the baseline measurement | |
No evidence of irregular astigmatism on corneal tomography | |
Anterior chamber depth ≥ 2.8 mm | |
Corneal endothelial cell count ≥ 2000/mm2 | |
Exclusion criteria | Progressive or unstable myopia and/or astigmatism |
Clinical or corneal topographic evidence of keratoconus | |
Residual, recurrent or active ocular disease and retinal disease | |
Previous corneal surgery | |
Taking systemic medications and systemically immunocompromised or systemic disease likely to affect wound healing, such as diabetes, connective tissue disease, and severe atopy; pregnant or nursing |