Fig. 5
From: Examining evidence of time-dependent treatment effects: an illustration using regression methods
Effect of aspirin on age at randomisation in PH and TD analysis for the MACE endpoint. The estimated age by treatment interaction effect from the PH model is the solid blue line with the shaded area indicating the 95% CI width. The interaction treatment effect from the TD model at yearly intervals is indicated by the green lines with colour intensity decreasing over time