Before radiation | During radiation | At the end of radiation (the final day of radiation) | Follow-up after treatment | |||||||
---|---|---|---|---|---|---|---|---|---|---|
Every week | The first year | The second and third years | The fourth year | From the fifth year | ||||||
Weeks 4–6 (first time) | The 3rd month | The 6th month | The 12th month | Every 3 months | Every 6 months | Every year | ||||
Written informed consent | √ | |||||||||
Medical history/physical examination | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ |
KPS, ECOG | √ | √ | √ | √ | √ | √ | √ | √ | √ | √ |
Pathological diagnosis | √ | |||||||||
Inclusion and exclusion criteria | √ | |||||||||
Peripheral blood routine examination | √ | √a | √ | √ | √ | √ | √ | √ | √ | √ |
Serum chemistry | √ | √a | √ | √ | √ | √ | √ | √ | √ | √ |
Urine and stool routine examination | √ | √a | √ | √a | √a | √a | √a | √a | √a | √a |
Levels of PSA, fPSA, testosterone, and NSE | √ | √ | √ | √ | √ | √ | √ | √ | √ | |
Tests for HIV, syphilis | √ | |||||||||
Tests for HBV, HCV | √ | |||||||||
Cardiac function examination | √ | |||||||||
CT of the chest | √ | √ | Annually | Annually | Annually | |||||
CT scan or ultrasound of the abdomen | √ | √ | √ | √ | √ | √ | √ | √ | √ | |
mpMRI of prostate | √ | √ | √ | √ | √ | √ | Annually | Annually | Annually | |
Bone scan examination | √a | √ | Annually | Annually | Annually | |||||
68Ga-PSMA PET/CT | √b | √b | √ | Annually | Annually | Annually | ||||
Evaluation of acute toxicities (NCI-CTACE) | √ | √ | √ | √ | √ | √ | ||||
Evaluation of late toxicities (RTOG/ EORTC) | √ | √ | √ | √ | √ | √ | ||||
EPIC | √ | √ | √ | √ | √ | √ | Annually | Annually | Annually | |
EQ-5D | √ | √ | √ | √ | √ | √ | Annually | Annually | Annually | |
IPSS | √ | √ | √ | √ | √ | √ | Annually | Annually | Annually |