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Table 3 Linear time effects for response rates used in simulation studies

From: Optimizing a Bayesian hierarchical adaptive platform trial design for stroke patients

 

t = 1

t = 2

t = 3

t = 4

θt

0.75

0.5

0.25

0

logit(Pjkt)

logit(PjkT) + 0.75

logit(PjkT) + 0.5

logit(PjkT) + 0.25

logit(PjkT) + 0

  1. t represents each interim analysis, θt represents time effects at different time points