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Table 2 A summary of five simulation scenarios without drift effect

From: Optimizing a Bayesian hierarchical adaptive platform trial design for stroke patients

Subgroup

Equal

Expected

Reversed

Extreme EVT

Single subgroup

 

PMM

PEVT

PMM

PEVT

PMM

PEVT

PMM

PEVT

PMM

PEVT

Large Core Only

0.1

0.1

0.1

0.25

0.25

0.1

0.1

0.30

0.25

0.45

Mild Deficit Only

0.7

0.7

0.7

0.84

0.84

0.7

0.7

0.89

0.84

0.84

Distal Occlusion Only

0.35

0.35

0.35

0.55

0.55

0.35

0.35

0.60

0.55

0.55

Distal Occlusion + Large core

0.25

0.25

0.25

0.45

0.45

0.25

0.25

0.50

0.45

0.45

Distal Occlusion + Mild Deficit

0.75

0.75

0.75

0.85

0.85

0.75

0.75

0.90

0.85

0.85