Table 2 Summary of recommendations for future RCT design and managing unexpected interruptions to research

• When designing future RCTs, we suggest choosing assessments with virtual-adaptability whenever possible, making specific note not only of the validity of these assessments when conducted remotely, but also their practical feasibility given ones’s participant population.

• When faced with unexpected interruptions to research, we further stress the importance of triaging paticipants to best preserve an RCTs primary outcome measures, while still honoring commitments to participants and keeping an open dialogue with them such that their voices can continue to guide decision-making.