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Table 1 Recommended sample size from interim SSR and course of action

From: Effect of high-flow nasal therapy on patient-centred outcomes in patients at high risk of postoperative pulmonary complications after cardiac surgery: a statistical analysis plan for NOTACS, a multicentre adaptive randomised controlled trial

Recommended sample size from interim SSR

Course of action

≤850

Continue recruitment to 850 patients

851–1152

Continue recruitment to the new recommended sample size

>1152

Continue recruitment to 1152 patients