From: Effect of high-flow nasal therapy on patient-centred outcomes in patients at high risk of postoperative pulmonary complications after cardiac surgery: a statistical analysis plan for NOTACS, a multicentre adaptive randomised controlled trial
Recommended sample size from interim SSR
Course of action
≤850
Continue recruitment to 850 patients
851–1152
Continue recruitment to the new recommended sample size
>1152
Continue recruitment to 1152 patients