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Table 2 Schematic diagram of the study procedures

From: Safety and effectiveness of delivering mass drug administration for helminths through the seasonal malaria chemoprevention platform among Senegalese children: study protocol for a randomised controlled trial

SMC cycle

1

2, 3 and 4

End of malaria season

Timelines (days)

Day 0–1

Day 0

Day 1

Days 2 and 3

Days 4–6

  

Study procedures

     

Passive surveillance

 

 Informed consent ± assent

X

     

 Enrolment and questionnaire administration to parent/caregivers

 

X

    

 Distribution of collecting bottles for stool sample

X

     

 Sample collection (finger-prick blood, urine, stool)

 

X

    

Randomisation

 

X

    

 Group 1: vitamin A + zinc

 

X

AQ + SP

AQ

  

 Group 2: PZQ + vitamin A

 

X

AQ + SP

AQ

  

 Group 3: ALB + PZQ

 

X

AQ + SP

AQ

  

 Safety assessments

 

X

X

X

X

 

Post-intervention survey

     

X

 Sample collection: finger-prick

     

X

 Sample collection: stool

     

X

 Sample collection: urine

     

X