Table 1 Treatment dosing regimen
Arm | Total daily dosage | Regimen | Total No of tablets daily |
|---|---|---|---|
FAVI active + nitazoxanide active | Day 1: FAVI = 3600mg | FAVI: 1st dose: 1800mg (9 tablets) 2nd dose: 1800mg (9 tablets) | Day 1: FAVI = 18 tablets |
OR | |||
FAVI active + nitazoxanide placebo | PLUS | PLUS | PLUS |
NITA = 1000 mg | LPV/r: 1st dose: 1000mg (2 tablets) 2nd dose: 1000mg (2 tablets) | NITA = 4 tablets | |
Day 2 to day 7: FAVI = 1600mg | FAVI: 1st dose: 400mg (2 tablets) 2nd dose: 400mg (2 tablets) 3rd dose: 400mg (2 tablets) 4th dose: 400mg (2 tablets) | Day 2 to Day 7: FAVI = 8 tablets | |
PLUS | PLUS | PLUS | |
NITA = 500mg | NITA: 1st dose: 500mg (1 tablet) 2nd dose: 500mg (1 tablet) 3rd dose: 500mg (1 tablet) 4th dose: 500mg (1 tablet) | NITA = 4 tablets | |