Table 1 Study procedures

Study coordination

 Obtain informed consent

X

 Screen for inclusion/exclusion

X

X

 Randomization

X

 Collect updated contact information

X

X

X

X

X

X

 Reimbursement

X

X

X

X

X

X

Questionnaires

 Demographic information

X

X

 Behavioral questionnaire

X

X

X

 HIV risk perception

X

X

X

X

X

 Social Harms and Intimate partner violence (IPV)

X

X

X

X

X

 Sexual behavior and exposure history

X

X

X

X

X

 PrEP adherence

X

X

X

X

X

 dPEP adherence (timeline follow-back calendar)

X ^a

X ^a

X ^a

X ^a

 Fertility intention

X

X

X

X

X

 Quality of Life

X

X

X

X

X

Clinical study care

 Medication review

X

X

X

X

X

X

 General symptom assessment

X

X

X

X

X

 WHO pregnancy checklist

X

X

X

X

X

X

 STI symptom assessment

X

X

X

X

X

X

 Supply condoms

X

X

X

X

X

X

 Contraception counseling and provision/referral

X

X

X

X

X

X

 Risk reduction counseling

X

X

X

X

X

X

 dPEP pill count and refill

X^a

X ^a

X ^a

X ^a

Sample collection

 HIV testing (rapid test)

X

X

X

X

X

 Urine pregnancy testing (rapid test)

X ^b

X

X ^b

X ^b

X ^b

X ^b

 Syphilis testing (serum rapid plasma reagin (RPR))

X

X

X

X

X

 Creatinine (serum)

X^b

X^b

X^b

X^b

X^b

 CT/NG testing and resistance (endocervical swabs) ^c

X

X

X

X

X

 Hair PrEP and doxycycline drug levels

X

X

X

X

X

 Trichomonas screening (vaginal swab)

X

X

X

X

X