Effectiveness of a clinical decision support system for hypertension management in primary care: study protocol for a pragmatic cluster-randomized controlled trial

Table 2 Outcomes of LIGHT and LIGHT-ACD trials

Outcomes	LIGHT	LIGHT-ACD
Primary	Appropriate (guideline-based) antihypertensive treatment rate	Absolute change in blood pressure at 9 months of different regimens of initial therapy
Secondary	Absolute change of systolic blood pressure at 9 months	Proportion of individuals with blood pressure controlled (SBP <140 mmHg and DBP <90 mmHg) at 9 months
	Blood pressure control rate (defined as SBP <140 mmHg and DBP <90 mmHg) at 9 months	Proportion of individuals with SBP <160 mmHg and DBP <100 mmHg at 9 months
	Acceptable (appropriate/non-appropriate but with proper reasons) antihypertensive treatment rate	Proportion of individuals who received monotherapy^a, dual therapy, triple therapy, and referral at 9 months
		Proportion of individuals with antihypertensive drug side-effects
		Proportion of individuals transferred to usual care for any reason
Exploratory	A composite of cardiac death, non-fatal stroke, and non-fatal myocardial infarction	Absolute change in blood pressure at 9 months of different protocols^a

Primary and secondary outcomes of LIGHT-ACD were assessed among initiating therapies; exploratory outcomes of LIGHT-ACD were assessed among protocols
SBP systolic blood pressure, DBP diastolic blood pressure
^a Only assessed in Population 1, who are not currently taking any antihypertensive medication with systolic blood pressure 140–159 mmHg, and initiated with monotherapy

ISSN: 1745-6215