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Table 4 The total number of people needed (with 1:1 randomisation) for detecting a given reduction in risk with 90% power and a significance level of 0.025 (one-sided)

From: Rifapentine and isoniazid for prevention of tuberculosis in people with diabetes (PROTID): protocol for a randomised controlled trial

 

Cumulative number of cases/1000 over 2 years of follow-up

RR

30/1000

40/1000

50/1000

0.4

2664

1982

1574

0.5

4106

3054

2424

0.6

6834

5082

4032