Skip to main content

Table 1 Ventilator settings

From: Effect of Automated Closed-loop ventilation versus convenTional VEntilation on duration and quality of ventilation in critically ill patients (ACTiVE) – study protocol of a randomized clinical trial

 

INTELLiVENT–ASV

Conventional ventilation

Settings

Enter patient’s gender and length (measured, not estimated) into the ventilator. Activate SpO2 and etCO2 sensors and select the INTELLiVENT mode. Set %MinVol, PEEP/CPAP, and oxygen controllers on “Automatic.” If applicable, patient condition is chosen (i.e., “ARDS,” “Chronic Hypercapnia,” or “Brain injury”). Select targets zones for etCO2 and SpO2 and select default alarm limits. Adjust targets for etCO2 and SpO2 when the results of the first arterial blood gas analysis are available

Enter patient’s gender and length (measured, not estimated) into the ventilator. Use any non-automated ventilation mode, e.g., (S)CMV, P-CMV and SPONT, depending on patient’s activity. Do not use semi or fully automated ventilation modes at any time (including the predecessor of INTELLiVENT–ASV named ASV)

Weaning

Enable the “Quick Wean” function

Check three times a day whether the patient accepts supported ventilation. Attempt supported ventilation when respiratory muscle activity is seen

during assist ventilation, or in case of patient–ventilator asynchrony

SBT

Automated SBT function can be used (left to discretion of the clinician)

SBTs using a T-piece or ventilation with minimal support (pressure support < 10 cm H2O). SBT is successful when respiratory rate < 35/breaths/min, SpO2 > 90%, increase < 20% of HR and BP without anxiety or diaphoresis (for at least 30 min)

  1. Abbreviations: SpO2 saturation of peripheral oxygen, etCO2 end-tidal carbon dioxide, %MinVol percentage of minute ventilation, PEEP positive end-expiratory pressure, CPAP continuous positive airway pressure, ARDS acute respiratory distress syndrome, (S)CMV synchronized controlled mandatory ventilation, P-CMV pressure-controlled mandatory ventilation, SPONT spontaneous breathing, ASV adaptive support ventilation, SBT spontaneous breathing trial, HR heart rate, BP blood pressure