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Table 2 Constructsa found to be prescriptive predictors of CMD treatment response in two or more studies

From: Study protocol for pragmatic trials of Internet-delivered guided and unguided cognitive behavior therapy for treating depression and anxiety in university students of two Latin American countries: the Yo Puedo Sentirme Bien study

I. Socio-demographics: Female, low parent education, marital status, distance of school from permanent residence, living arrangement while at school, employment while at school

II. Behavioral health history, triggers, and symptoms: Symptoms of generalized anxiety disorder, panic disorder, separation anxiety disorder, social phobia, post-traumatic stress disorder, major depressive disorder, adjustment disorder with anxiety and/or depressed mood, insomnia, multimorbidity, history of suicidality, early age of onset, chronicity, high baseline severity, endogenous (depression), number prior/recurrent episodes, high psychomotor symptoms/low energy (depression), avoidance (experiential and behavioral), fear of negative evaluation, role impairment, personality disorder (Borderline Cluster C), psychotic-like symptoms

III. Stress and adversity: Childhood maltreatment/trauma, parental bonding, high stress, interpersonal loss, poor physical functioning, poor cognitive functioning, poor social functioning, poor social support/relationships

IV. Personality traits/temperament: Agreeableness, alexithymia, anxiety sensitivity, attentional control, attributional style, catastrophic cognitions, conscientiousness, cognitive distortions, emotional regulation, extraversion, hopelessness, low openness to experience, negative affect/neuroticism, non-secure attachment style, perceived control, stress reactivity, temperament

V. Treatment engagement and related constructs: Adherence, health literacy, preferences for type of treatment, therapeutic alliance

VI. Other: High cognitive dysfunction/low intelligence

  1. aSee [60,61,62,63,64] for reviews of relevant studies