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Table 1 PICOS format of the research question

From: Efficacy and safety of Mydriatic Microdrops for Retinopathy Of Prematurity Screening (MyMiROPS): study protocol for a non-inferiority crossover randomized controlled trial

Population

Preterm infants undergoing retinopathy of prematurity screening

Intervention

Microdrops of phenylephrine 1.67% and tropicamide 0.33%

Comparator

Standard drops of phenylephrine 1.67% and tropicamide 0.33%

Outcomes

Efficacy: millimeters of pupil diameter

Safety: occurrence of systemic adverse events and systemic absorption

Study type

Non-inferiority, crossover, randomized controlled trial