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Fig. 5 | Trials

Fig. 5

From: Study of effect of nimodipine and acetaminophen on postictal symptoms in depressed patients after electroconvulsive therapy (SYNAPSE)

Fig. 5

Schematic representation of time schedule and applied measures during SYNAPSE. At baseline, the psychometry battery, EEG and MRI measurements are taken. During and after a maximum of 13 ECT sessions (the first session will be without intervention; in the other 12 ECT sessions, the interventions are applied), intermittent ROT (interval: 5 min) and continuous EEG measures are recorded. Within 1 h after 3 ECT sessions, MRI will take place (one for each intervention). The psychometric measures, EEG, and MRI measurements will be repeated at follow-up within 2 weeks after completion of the ECT course and after 3 months. ROT, reorientation time. ASL, arterial spin labelling. PCM, paracetamol (acetaminophen). ND, nimodipine. NI, no intervention. EEG, electroencephalography. ECT, electroconvulsive therapy

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