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Table 1 Trial inclusion and exclusion criteria

From: Communication Bridge™-2 (CB2): an NIH Stage 2 randomized control trial of a speech-language intervention for communication impairments in individuals with mild to moderate primary progressive aphasia

Applies to Both the Person with PPA and Co-Enrolled Healthy Adult Communication Partner

Adults (18+ years of age). No maximum age limit.

English is primary language used in daily communication activities (self-report)

Adequate hearing (aided or unaided) for communicating with others in a crowded room (self-report)

Adequate vision (aided or unaided) for reading a newspaper, or other functional materials (self-report)

Able to pass technology screeninga and demonstrates sufficient knowledge for use of video conference and Communication BridgeTM web application use (with or without training)

Applies to Person with PPA Only

Geriatric Depression Scale score ≤ 9 

Mild-moderate language symptoms informed by a structured interview with a speech-language pathologist and by the following assessments: BDAE Spontaneous Speech task (‘Cookie Theft’ stimulus) scored using an adapted version of the WAB-R scoring system [61]; BDAE Repetition subtest: high probability words; NACC-FTLD Module noun naming subtest ≥ 80% (if score is 80 or lower, the NACC-FTLD word-picture matching is used to verify severity level).

  1. WAB-R Western Aphasia Battery Revised [62], BDAE Boston Diagnostic Aphasia Exam [63], NACC-FTLD National Alzheimer’s Coordinating Center-Frontotemporal Lobar Degeneration assessment modules [64, 65]
  2. aDenotes study-specific forms/instruments available with the CB2 Manual of Procedures [66]