Skip to main content
Fig. 1 | Trials

Fig. 1

From: Tolerance induction through non-avoidance to prevent persistent food allergy (TINA) in children and adults with peanut or tree nut allergy: rationale, study design and methods of a randomized controlled trial and observational cohort study

Fig. 1

The study diagram shows the flow of the screened subjects (1–67 years of age) after the initial double-blind, placebo-controlled food challenge (DBPCFC) into the randomized controlled trial (allergic participants) or the cohort study (tolerant participants). Subjects of the randomized controlled trial will be randomized 1:1 in the liberated diet group (allergen consumption below the individual threshold level) or the complete allergen avoidance group. After 12 months, all participants will be re-assessed for clinical tolerance development or maintenance of tolerance respectively

Back to article page