Sponsor related | Site/investigator related | Patient related | Collaboration related | Start-up relateda |
---|---|---|---|---|
Trial protocol | Access to patients | Patients’ medical need for new treatments | Sponsor-site-patient collaboration | Ethics committee evaluation |
Trial preparation and feasibility evaluations | Investigators’ motivation for trials and commitment to recruitment | Patients’ role in their care and attitudes to clinical trials | Site contracts | |
Site resources, setup, and experience |