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Table 2 Cumulative incidence of PPH outcome measures and their diagnostic accuracy for early shock defined as shock index ≥1

From: Postpartum haemorrhage in anaemic women: assessing outcome measures for clinical trials

PPH definition

SI ≥ 1

SI < 1

Total

Sensitivity

Specificity

n

(%)

n

(%)

N

(%)

Clinical diagnosis of PPH

 Yes

109

(31)

208

(5)

317

(7)

31%

95%

 No

240

(69)

3956

(95)

4196

(93)

  

 Total

349

(100)

4164

(100)

4513

(100)

  

Estimated blood loss ≥ 500 ml

 Yes

95

(27)

274

(7)

369

(8)

27%

93%

 No

254

(73)

3890

(93)

4144

(92)

  

 Total

349

(100)

4164

(100)

4513

(100)

  

Total blood volume lost ≥ 15%

 Yes

48

(14)

69

(2)

117

(3)

14%

98%

 No

301

(86)

4095

(98)

4396

(97)

  

 Total

349

(100)

4164

(100)

4513

(100)

  

Peripartum Hb drop ≥ 20 g/La

 Yes

47

(14)

111

(3)

158

(4)

14%

97%

 No

297

(86)

3990

(97)

4287

(96)

  

 Total

344

(100)

4101

(100)

4445

(100)

  

Peripartum Hb drop ≥ 10%a

 Yes

105

(31)

604

(15)

709

(16)

31%

85%

 No

239

(69)

3497

(85)

3736

(84)

  

 Total

344

(100)

4101

(100)

4445

(100)

  

Calculated blood loss ≥ 1000 mla

 Yes

70

(20)

298

(7)

368

(8)

20%

93%

 No

274

(80)

3799

(93)

4073

(92)

  

 Total

344

(100)

4097

(100)

4441

(100)

  

RBC transfusion within 24 h after delivery

 Yes

119

(34)

1010

(24)

1129

(25)

34%

76%

 No

226

(66)

3121

(76)

3347

(75)

  

 Total

345

(100)

4131

(100)

4476

(100)

  

IV fluid within 24 h after delivery

 Yes

200

(58)

1716

(42)

1916

(43)

59%

58%

 No

139

(40)

2331

(56)

2470

(55)

  

 Total

339

(98)

4047

(98)

4386

(98)

  

TXA within 24 h after delivery

 Yes

87

(25)

169

(4)

256

(6)

25%

96%

 No

262

(76)

3994

(97)

4256

(95)

  

 Total

349

(101)

4163

(101)

4512

(101)

  

Postpartum uterotonics

 Yes

133

(39)

1174

(28)

1307

(29)

38%

72%

 No

216

(63)

2990

(72)

3206

(72)

  

 Total

349

(101)

4164

(101)

4513

(101)

  
  1. PPH postpartum haemorrhage, SI shock index, Hb haemoglobin, RBC red blood cell, IV intravenous, TXA tranexamic acid
  2. aPostpartum Hb corrected for RBC transfusions and IV fluids received between randomisation and postpartum Hb test