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Table 3 The Mini-Mental State Examination scores at T0, T1, T2, T3, T4, and T5 in the two groups. The MMSE scores were lower at T1 and T2 compared to T0 in the two groups (P < 0.001). The MMSE scores were similar between the two groups at T0, T1, T2, T3, T4, and T5 (P > 0.05)

From: The effects of remifentanil-propofol combined with dexmedetomidine on cognitive dysfunction in elderly patients after ureteroscopic holmium laser lithotripsy: a double-blind randomized controlled trial

Time points

PR group

PRD group

F values

P values

T0

25.4 ± 2.2

25.5 ± 2.5

0.431

0.700

T1

20.7 ± 2.1*

21.3 ± 2.5*

0.423

0.183

T2

22.8 ± 2.0*

23.3 ± 2.0*

0.367

0.223

T3

25.0 ± 2.2

25.2 ± 2.6

0.432

0.644

T4

25.1 ± 2.2

25.2 ± 2.4

0.421

0.664

T5

25.3 ± 2.2

25.4 ± 2.5

0.429

0.756

F values

129.34

105.55

–

–

P values

0.000

0.000

–

–

  1. Values are mean ± SD
  2. PR propofol-remifentanil, PRD propofol-remifentanil and dexmedetomidine, T0 before the induction of anesthesia, T1 3 h after surgery, T2 6 h after surgery, T3 24 h after surgery, T4 48 h after surgery, T5 72 h after surgery
  3. *P < 0.001 vs. T0