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Table 2 Confidence interval calculations and decision on non-inferiority confidence interval based test

From: Non-inferiority test for a continuous variable with a flexible margin in an active controlled trial: an application to the “Stratall ANRS 12110 / ESTHER” trial

 

One-sided CI

Two-sided CI

 

Case of LOCF

 

CLIN−LAB+ΔL(LAB)

− 5 to∞

− 10 to52

Decision

Inferiority

Inferiority

 

Case of observed data

 

CLIN−LAB+ΔL(LAB)

7 to∞

1 to72

Decision

Non-inferiority

Non-inferiority

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ISSN: 1745-6215