The effect of tourniquet application on the morphology and function of quadriceps in patients undergoing total knee arthroplasty: study protocol for a single-blind randomized controlled trial

Table 1 Schedule of enrollment, interventions, and assessments

Time point		Study period
		Enrollment	Allocation	Post-allocation
		Enrollment	Allocation	t1	t2	t3	t4	t5	t6	t7	t8
Enrollment	Eligibility screen	X
	Informed consent	X
	Randomization		X
Interventions	Tourniquet group				X
Interventions	Non-tourniquet group				X
Assessments	Demographic data			X
	Quadriceps thickness			X			X
	Quadriceps stiffness			X			X
	Isokinetic muscle strength test								X
	3D gait analysis								X
	Posture stability testing								X
	Thigh circumference			X		X	X
	VAS score					X	X	X	X
	Opioid consumption						X
	Knee function score			X						X	X
	Postoperative satisfaction score									X	X
	Operation time				X
	Intraoperative blood loss				X
	Perioperative blood loss						X
	Blood transfusion rate					X	X	X
	d-dimer			X		X	X
	C-reactive protein			X		X	X
	Complications					X	X	X	X	X	X

t1 before the operation, t2 in operation, t3 1 day after the operation, t4 3 days after the operation, t5 2 weeks after the operation, t6 6 weeks after the operation, t7 3 months after the operation, t8 1 year after the operation

ISSN: 1745-6215