PROPHYlactic Implantation of BIOlogic Mesh in peritonitis (PROPHYBIOM): a prospective multicentric randomized controlled trial

Table 1 Time and event chart

Nomenclature	Visit 1	Visit 2	Visit 3	Visits 4, 5, and 6
Nomenclature	Screening	Treatment	Discharge	Follow-up
	Screening, baseline	Surgery	Discharge	Follow-up
Informed consent	√
Inclusion/exclusion criteria	√
Demographic data (sex, age, weight, height, BMI)	√
Medical history/concomitant illness	√
Physical examination	√		√	√
ASA classification	√
Vital signs	√	√
Body weight and height	√
ECG (12 lead)	√
Hematology and coagulation parameters	√		√
Blood chemistry	√		√
Antibiotic therapy	√
Start of LMW heparin	√
Concomitant medication^a	√ continuously
Start and end of surgery		√
Site and length of incision		√
Peritonitis grade assessment		√
Peritoneal fluid sampling for microbiological examination		√
Contamination assessment		√
Intestinal resection		√
Stoma creation		√
Surgical complications		√
Surgical drain placement		√
Surgery report		√
Time of drain removal			√
Length of stay in hospital			√
Post-surgical complications			√	√
Abdominal wall ultrasound				√
Adverse events	√ continuously

^aThis includes use of any blood transfusions that should be inserted in the CRF as type (red blood cells. FFP, platelets)

ISSN: 1745-6215