Skip to main content
Fig. 2 | Trials

Fig. 2

From: CeRebrUm and CardIac Protection with ALlopurinol in Neonates with Critical Congenital Heart Disease Requiring Cardiac Surgery with Cardiopulmonary Bypass (CRUCIAL): study protocol of a phase III, randomized, quadruple-blinded, placebo-controlled, Dutch multicenter trial

Fig. 2

Participant timeline. Black circles (●) indicate neonates with a prenatal CCHD diagnosis. White circles (○) indicate neonates with a postnatal CCHD diagnosis. *In included subjects from the Erasmus Medical Center Rotterdam and University Medical Center Utrecht. **In the first 24 subjects with a prenatal CCHD diagnosis in UMC Utrecht. aEEG, amplitude-integrated electroencephalography; Bayley-III-NL, Bayley Scales of Infant and Toddler Development - Third Edition - Dutch Norms; CCHD, critical congenital heart disease; h, hours; HTA, health technology assessment; MRI, magnetic resonance imaging; NIRS, near-infrared spectroscopy; TAPQoL, TNO-AZL preschool children’s health-related quality of life

Back to article page

Trials

ISSN: 1745-6215